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產品詳情
操作說明
注意事項
Product Information
|
Description |
CBX2 rabbit polyclonal antibody |
|
Protein full name |
Chromobox protein homolog 2 |
|
Synonyms |
M33, Modifier 3 protein, Cbx2, CDCA6, MOD2, SRXY5, Polycomb |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CBX2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
55 kDa |
|
Observed MW. |
55 kDa |
|
Uniprot ID |
Q14781, P30658 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
liver, spleen, testis |
Background
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development . PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility . Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) . Plays a role in the lineage differentiation of the germ layers in embryonic development . Involved in sexual development, acting as activator of NR5A1 expression .
Images
|
|
Western blot analysis of CBX2 (GB112013) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室