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400-1016-218
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- 手機：400-1016-218
- Q Q：355185756
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- 地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室
產品詳情
操作說明
注意事項
Product Information
|
Description |
LAMTOR2 rabbit polyclonal |
|
Protein full name |
Ragulator complex protein LAMTOR2 |
|
Synonyms |
Lamtor2, ENDAP, Endosomal adaptor protein p14, MAPBPIP, MAPKSP1AP, P14, ROBLD 3 |
|
Immunogen |
Recombinant protein corresponding to Mouse LAMTOR2 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cytoplasm |
|
Uniprot ID |
Q9JHS3 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
IHC |
Mouse, Rat |
1: 500-1: 2500 |
brain, lung, stomach |
|
IF |
Mouse, Rat |
1: 250-1: 500 |
brain, lung, stomach |
Background
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Images
|
Immunohistochemistry analysis of paraffin-embedded mouse brain using LAMTOR2 (GB11935) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded rat brain using LAMTOR2 (GB11935) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded mouse lung using LAMTOR2 (GB11935) at dilution of 1: 1000 |
|
Immunohistochemistry analysis of paraffin-embedded rat lung using LAMTOR2 (GB11935) at dilution of 1: 1500 |
|
Immunohistochemistry analysis of paraffin-embedded mouse stomach using LAMTOR2 (GB11935) at dilution of 1: 1500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室